American Airlines flights from Panama City
expand_more
1 Adult, Economy class
expand_moreexpand_more
today
today
Popular flights from Panama City
flight_takeoff
flight_land
$
Panama City (ECP)to
Dallas (DFW)04/22/26 - 04/29/26from$287Fare subject to changesUpdated: 3 hours agoRound tripEconomy
Panama City (ECP)to
Charlotte (CLT)05/02/26 - 05/09/26from$353Fare subject to changesUpdated: 12 hours agoRound tripEconomy
Panama City (ECP)to
Washington, D.C. (DCA)05/02/26 - 05/09/26from$365Fare subject to changesUpdated: 11 hours agoRound tripEconomy
Panama City (ECP)to
Chicago (ORD)04/22/26 - 04/29/26from$271Fare subject to changesUpdated: 2 hours agoRound tripEconomy
Panama City (ECP)to
Honolulu (HNL)04/28/26 - 05/05/26from$737Fare subject to changesUpdated: 1 hour agoRound tripEconomy
Panama City (ECP)to
Indianapolis (IND)05/01/26 - 05/08/26from$291Fare subject to changesUpdated: 9 hours agoRound tripEconomy
Panama City (ECP)to
Austin (AUS)05/02/26 - 05/09/26from$304Fare subject to changesUpdated: 5 hours agoRound tripEconomy
Panama City (ECP)to
San Diego (SAN)04/21/26 - 04/28/26from$375Fare subject to changesUpdated: 8 hours agoRound tripEconomy
Panama City (ECP)to
Philadelphia (PHL)04/21/26 - 04/28/26from$291Fare subject to changesUpdated: 2 hours agoRound tripEconomy
Panama City (ECP)to
Hartford (BDL)04/21/26 - 04/28/26from$351Fare subject to changesUpdated: 6 hours agoRound tripEconomy
*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.
Find more deals on flights from Panama City
flight_takeoff
flight_land
$
Panama City (ECP)to
Dallas (DFW)
06/03/26 - 06/10/26
Round trip
Economy
from
$277Fare subject to changes
Updated: 3 hours ago
Panama City (ECP)to
Charlotte (CLT)
06/09/26 - 06/16/26
Round trip
Economy
from
$353Fare subject to changes
Updated: 12 hours ago
Panama City (ECP)to
Washington, D.C. (DCA)
06/16/26 - 06/23/26
Round trip
Economy
from
$355Fare subject to changes
Updated: 11 hours ago
Panama City (ECP)to
Chicago (ORD)
05/05/26 - 05/12/26
Round trip
Economy
from
$271Fare subject to changes
Updated: 2 hours ago
Panama City (ECP)to
Honolulu (HNL)
05/27/26 - 06/03/26
Round trip
Economy
from
$732Fare subject to changes
Updated: 1 hour ago
Panama City (ECP)to
Indianapolis (IND)
05/21/26 - 05/28/26
Round trip
Economy
from
$291Fare subject to changes
Updated: 2 minutes ago
*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.
With an expansive network of destinations, your world is a flight away
To search for a great fare, start by selecting your departure city. Looking to book using miles? Try our miles finder map.