American Airlines flights from United States to Panama

Popular flights with American Airlines

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*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

American Airlines flights from the United States to Panama

Business class flights from United States to Panama

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Miami (MIA)to

Panama City (PTY)
02/22/26 - 02/28/26

Round trip

Business / First

from
$845Fare subject to changes
Updated: 12 hours ago

Dallas (DFW)to

Panama City (PTY)
03/10/26 - 03/14/26

Round trip

Business / First

from
$1,209Fare subject to changes
Updated: 8 hours ago

Charlotte (CLT)to

Panama City (PTY)
01/05/26 - 01/13/26

Round trip

Business / First

from
$1,290Fare subject to changes
Updated: 4 hours ago

Philadelphia (PHL)to

Panama City (PTY)
12/30/25 - 01/05/26

Round trip

Business / First

from
$1,521Fare subject to changes
Updated: 13 hours ago

Baltimore (BWI)to

Panama City (PTY)
01/24/26 - 01/31/26

Round trip

Business / First

from
$1,582Fare subject to changes
Updated: 17 hours ago

Los Angeles (LAX)to

Panama City (PTY)
01/07/26 - 01/14/26

Round trip

Business / First

from
$3,870Fare subject to changes
Updated: 9 hours ago

Phoenix (PHX)to

Panama City (PTY)
12/29/25 - 01/02/26

Round trip

Business / First

from
$4,161Fare subject to changes
Updated: 6 hours ago

Seattle (SEA)to

Panama City (PTY)
02/01/26 - 02/28/26

Round trip

Business / First

from
$2,275Fare subject to changes
Updated: 11 hours ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Find deals on United States to Panama flights

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Miami (MIA)to

Panama City (PTY)
02/22/26 - 02/28/26

Round trip

Economy

from
$349Fare subject to changes
Updated: 12 hours ago

Dallas (DFW)to

Panama City (PTY)
03/02/26 - 03/07/26

Round trip

Economy

from
$524Fare subject to changes
Updated: 7 hours ago

Charlotte (CLT)to

Panama City (PTY)
02/19/26 - 02/22/26

Round trip

Economy

from
$543Fare subject to changes
Updated: 13 hours ago

Baltimore (BWI)to

Panama City (PTY)
01/24/26 - 01/31/26

Round trip

Economy

from
$506Fare subject to changes
Updated: 17 hours ago

Phoenix (PHX)to

Panama City (PTY)
06/28/26 - 07/04/26

Round trip

Economy

from
$1,155Fare subject to changes
Updated: 17 hours ago

Seattle (SEA)to

Panama City (PTY)
02/01/26 - 02/28/26

Round trip

Economy

from
$664Fare subject to changes
Updated: 11 hours ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

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Top United States to Panama routes