American Airlines flights from Destin

Popular flights from Destin

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  • Destin (VPS)to

    Boston (BOS)
    04/21/26 - 04/28/26
    from
    $225Fare subject to changes
    Updated: 8 hours ago
    Round trip
    Economy

    Destin (VPS)to

    Chicago (ORD)
    05/02/26 - 05/09/26
    from
    $375Fare subject to changes
    Updated: 13 hours ago
    Round trip
    Economy

    Destin (VPS)to

    Los Angeles (LAX)
    04/21/26 - 04/28/26
    from
    $381Fare subject to changes
    Updated: 5 hours ago
    Round trip
    Economy

    Destin (VPS)to

    Las Vegas (LAS)
    04/21/26 - 04/28/26
    from
    $381Fare subject to changes
    Updated: 15 hours ago
    Round trip
    Economy

  • Destin (VPS)to

    Orange County (SNA)
    05/02/26 - 05/09/26
    from
    $395Fare subject to changes
    Updated: 41 minutes ago
    Round trip
    Economy

    Destin (VPS)to

    Wichita (ICT)
    04/28/26 - 05/05/26
    from
    $339Fare subject to changes
    Updated: 1 hour ago
    Round trip
    Economy

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Find more deals on flights from Destin

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Destin (VPS)to

Dallas (DFW)
05/19/26 - 05/26/26

Round trip

Economy

from
$262Fare subject to changes
Updated: 6 hours ago

Destin (VPS)to

Miami (MIA)
05/05/26 - 05/12/26

Round trip

Economy

from
$218Fare subject to changes
Updated: 1 hour ago

Destin (VPS)to

Charlotte (CLT)
05/02/26 - 05/09/26

Round trip

Economy

from
$346Fare subject to changes
Updated: 6 hours ago

Destin (VPS)to

Phoenix (PHX)
06/09/26 - 06/16/26

Round trip

Economy

from
$335Fare subject to changes
Updated: 5 hours ago

Destin (VPS)to

Boston (BOS)
06/02/26 - 06/09/26

Round trip

Economy

from
$225Fare subject to changes
Updated: 8 hours ago

Destin (VPS)to

Chicago (ORD)
05/20/26 - 05/27/26

Round trip

Economy

from
$356Fare subject to changes
Updated: 13 hours ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

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Destinations from Destin