American Airlines flights to Panama City from $159*

Popular flights to Panama City on American Airlines

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*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

American Airlines flights to Panama City from **Flights.FromLowestPrice***

Find deals on flights to Panama City

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Dallas (DFW)to

Panama City (ECP)
08/05/25 - 08/12/25

Round trip

Economy

from
$189Fare subject to changes
Updated: 2 hours ago

Washington, D.C. (DCA)to

Panama City (ECP)
08/06/25 - 08/13/25

Round trip

Economy

from
$207Fare subject to changes
Updated: 3 hours ago

Cincinnati (CVG)to

Panama City (ECP)
08/05/25 - 08/12/25

Round trip

Economy

from
$221Fare subject to changes
Updated: 1 minute ago

Philadelphia (PHL)to

Panama City (ECP)
08/24/25 - 08/31/25

Round trip

Economy

from
$323Fare subject to changes
Updated: 3 hours ago

Charlotte (CLT)to

Panama City (ECP)
07/05/25 - 07/12/25

Round trip

Economy

from
$313Fare subject to changes
Updated: 10 hours ago

Fayetteville (XNA)to

Panama City (ECP)
07/08/25 - 07/15/25

Round trip

Economy

from
$249Fare subject to changes
Updated: 12 hours ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Panama City routes with American Airlines